ANCA-negative Churg-Strauss Syndrome

ANCA-positive Churg-Strauss syndrome with renal failure.

Churg–Strauss syndrome was described in 1951 as a granulomatous variant of polyarteritis nodosa with eosinophilic tissue infiltration [1]. The clinical presentation corresponds to that of a systemic vasculitis involving one or more extrapulmonary organs with asthma and peripheral blood eosinophilia in excess of 1.5×109/l [2 ]. Our 56-year-old patient was primarily treated for spastic bronchitis...

Central retinal artery occlusion in a patient with ANCA-negative Churg-Strauss syndrome

Ocular involvement in Churg-Strauss syndrome is infrequent. We describe the case of a 54-year-old woman with eosinophilia and involvement of the respiratory tract, skin, and peripheral nervous system, fulfilling the American College of Rheumatology criteria for Churg-Strauss syndrome. The patient presented with acute, painless vision loss in her right eye. Central retinal artery occlusion (CRAO...

Churg-Strauss syndrome.

Churg-strauss syndrome.

First described in 1951 as an allergic and granulomatous angiitis, Churg-Strauss syndrome (CSS) is a small-vessel vasculitis. Mean age at the time of diagnosis is approximately 50 years, with a sex ratio around 1. Asthma is the central feature of CSS and precedes the systemic manifestations in almost all cases, whereas 70% of the patients have maxillary sinusitis, allergic rhinitis, and/or sinu...

Churg-Strauss Syndrome

Pulmonary: asthma, pneumonitis and haemoptysis. Upper respiratory tract: allergic rhinitis, paranasal sinusitis, nasal polyposis. Cardiac involvement is common. [6]This includes heart failure, myocarditis and myocardial infarction. [7] Skin: purpura, skin nodules, leukocytoclastic angiitis with palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. Renal: glomer...